With increasing urban populations and limited arable land for horticultural production, food security is becoming a growing concern worldwide. Hydroponic systems, defined as cultivation techniques involving soilless media, offers a potential solution to enhance food security by increasing urban food production. For this study three tabletop hydroponic systems, viz., iDOO, INT, and MUFGA were used for cultivating of Rex butterhead lettuce (Lactuca sativa). Three seeding trays, with 200 cells each embedded with rockwool were sowed 9 days before being transplanted into the hydroponic units. Growth parameters were recoded for 6 weeks, viz., plant height, and leaf number, length, and width. Visual rating (1 through 10) were also recorded. Additionally, the pH and the electrical conductivity (EC) of the nutrient solution were monitored. Following the harvest, fresh weight and root length were recorded. The data collected was subjected to ANOVA. Results indicated that plants grown in MUFGA unit were significantly (p