Potato (Solanum tuberosum L.) crops require a high amount of potassium (K) to achieve the ideal yield and quality. However, the effect of K fertilization on potato tuber nutritional value is largely unknown. Based on the tubers from two-year field trials on a Quincy loamy fine sand soil in the Columbia Basin of Oregon, we evaluated yield, specific gravity, nutritional contents (i.e., ascorbic acid, tyrosine, chlorogenic acid, tryptophan, phenylalanine), and nutrient contents (nitrogen [N], phosphorus [P], K, and sulfur [S]) of three potato varieties (Clearwater Russet, Russet Burbank, and Umatilla Russet) under three K rates (0, 448, and 897 kg ha-1). Our results showed that the K application increased the yield of >170 g tubers but had no considerable effect on the total tuber yield. The application of K tended to decrease specific gravity regardless of varieties and years. Russet Burbank had the lowest specific gravity while Clearwater Russet had the highest one. Most of the nutritional contents were higher in 2020 than in 2021. Russet Burbank generally had the highest nutritional contents except for ascorbic acid compared to two other varieties. The application of K generally did not affect tuber nutritional contents but reduced the amounts of tyrosine in Clearwater Russet and Umatilla Russet in 2020. Fertilization of K resulted in an enhanced K content in the tuber, with the highest K application rate exhibiting a 35% increase in K compared to the control. However, it did not have any discernible effects on N, P, and S contents in the tubers. The tuber P and S were lower in Russet Burbank than other varieties. In general, there is no strong relationship between K fertilization and tuber nutritional contents.