The retention and recruitment of freshmen students transitioning to higher education or transferring to new institutions represent significant challenges for universities nationwide. Research underscores the mental health challenges encountered by students upon entering higher education, highlighting the necessity for effective resolution strategies. This study aimed to assess the impact of a plant distribution and care program on first-year university student retention, as well as levels of depression, stress, anxiety, and loneliness. The study employed a treatment and control group, both of which underwent pretest and posttest assessments using the DASS-21 and UCLA Loneliness scale, along with demographic information and prior experiences with mental health issues and plants. Recruitment for both groups was conducted through convenience sampling across university students. The treatment group participated in an 8-week program where they received designated plants and were instructed to care for them within their dormitories using plant care tips provided through an online platform. Additionally, they engaged in greenhouse activities. Conversely, the control group underwent pretest and posttest assessments at the same intervals as the treatment group, without any intervention. Results revealed a significant improvement in mental health among participants in the treatment group, despite data collection coinciding with final semester exams. Conversely, the control group exhibited no discernible differences between pretest and posttest assessments. These findings suggest that houseplants may serve as a viable means to mitigate stress, depression, anxiety, and loneliness among incoming university students.