Feverfew, a member of the Asteraceae family, has a long history of traditional use for various health purposes, including anxiety and depression management, and alleviating arthritis and inflammation. Feverfew consists of a specific chemical compound named parathenolide which is a phytochemical naturally found in Tanacetum parthenium, which plays a significant role in being responsible for feverfew’s anti-inflammatory effects. This study aims to investigate the effect of the temperature changes in parathenolide accumulation among two varieties Matricaria Tetra White and Matricaria Tetra Virgo Feverfews based on their genetic differences. Feverfew cultivars will be grown in a container containing potting mix which has enough nutrients for plant growth and development. The two varieties will be randomized with each variety receiving varying temperature differences (low, medium, and high). The accumulation for parathenolide will be analyzed using HPLC analysis to evaluate the accumulation of the phytochemical in each variety in response of the differences in temperatures. Among the phytochemicals of interested in this study include an understanding the effect of temperature on the accumulation and synthesis of the phytonutrients can highly assist scientists and health care professionals to increase and promote medicinal plants. Feverfew can benefit low-income communities like urban areas where majority of the community members are incapable to afford medication that can treat sickness such as anxiety and depression.
